Frequency of train-of-four stimulation influences neuromuscular response

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Frequency of train-of-four stimulation influences neuromuscular response.

We have compared the effects of two different frequencies of train-of-four stimulation of the ulnar nerve (2-Hz stimulation once every 10 or 20 s) on onset time and potency of atracurium, vecuronium and mivacurium during balanced anaesthesia. The adductor pollicis EMG was recorded simultaneously in both hands of 24 children aged 2-12 yr. After administration of an ED50 dose of each blocker, ons...

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Train-of-four to monitor neuromuscular blockade?

1 Campbell M. Natural history of coarctation of the aorta. Br Heart J 1970; 32:633–640 2 Perloff JK. Coarcation of the aorta. In: The clinical recognition of congenital heart disease. Philadelphia, PA: W.B. Saunders, 1999; 132–169 3 Behl PR, Sante P, Blesovsky A. Isolated coarctation of the aorta: surgical treatment and late results: eighteen years’ experience. J Cardiovasc Surg 1988; 29:509–51...

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Reversal of neuromuscular blockade with sugammadex at the reappearance of four twitches to train-of-four stimulation.

BACKGROUND Doses of sugammadex required to reverse deep, moderate, and shallow rocuronium-induced neuromuscular blockade have been established. However, no adequate doses for the reversal of reappearance of four twitches of train-of-four (TOF) stimulation (threshold TOF-count-four) have been established. METHODS This single-center, randomized, controlled, double-blind, four-groups parallel-ar...

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Nondepolarizing neuromuscular blocking drugs and train-of-four fade.

The aim of this study was to examine differences in prejunctional effects of different relaxants by measuring the train-of-four (TOF) fade during the onset and recovery of neuromuscular block. The relaxants studied were atracurium (225 micrograms.kg-1), mivacurium (65 micrograms.kg-1) rocuronium (300 micrograms.kg-1) and vecuronium (40 micrograms.kg-1). The TOF ratios were measured at approxima...

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Effect of tetanic stimulation on subsequent train-of-four responses at various levels of vecuronium-induced neuromuscular block.

Tetanic stimulation influences subsequent neuromuscular responses. In addition, the tetanus-induced changes in neuromuscular responses differ according to the level of neuromuscular block at which tetanic stimulation is delivered. We studied the tetanus-induced effect on subsequent train-of-four (TOF) responses at various levels of vecuronium-induced neuromuscular block in 45 anaesthetized pati...

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ژورنال

عنوان ژورنال: British Journal of Anaesthesia

سال: 1994

ISSN: 0007-0912

DOI: 10.1093/bja/72.6.686